Personnel

Hunter Elliott
Director
LHRRB 105

Hunter studied physics and chemistry as an undergrad at The Colorado College, and he received his Ph.D. in biophysics from The Scripps Research institute, developing image analysis algorithms to study cell migration in the laboratory of Professor Gaudenz Danuser. Hunter has been a member of IDAC since its founding in October 2012.

Clarence Yapp
Imaging and Analysis Research Associate
LHRRB 105
Clarence studied Mechatronics Engineering and pursued a MSc and DPhil from the University of Oxford, England. At the Structural Genomics Consortium, he developed image-based high-content cellular assays for identifying potent small molecule inhibitors against epigenetic targets. He also served as the microscopy facility manager at the Botnar Research Centre. At IDAC, Clarence aims to apply his interests in new microscopy techniques and unsupervised machine learning image analysis algorithms to solve problems.
Marcelo Cicconet
Senior Image Analysis Scientist / Software Engineer
LHRRB 105

Marcelo obtained a PhD in Applied Mathematics from IMPA in Rio de Janeiro. After a postdoc in Computer Vision for human-robot interaction at Georgia Tech, he moved to New York University and focused on image analysis for Biology, being the main link of a collaboration between Kris Gunsalus (Biology department) and Davi Geiger (Courant Institute). At IDAC, Marcelo intends to continue his work in biological image analysis, while keeping an eye out for the improvements on basic Computer Vision and Machine Learning algorithms that such applications can inspire.

Fellows

Srigokul Upadhyayula
Postdoctoral Research Fellow, Kirchausen Lab
200 Longwood Ave., WAB138 Boston, MA 02115

Gokul is currently a postdoctoral fellow in the Kirchhausen lab at the Dept. of Cell Biology at Harvard Medical School and PCMM at Boston Children’s Hospital. Before starting his postdoc, he received his Ph.D. in Biochemistry and M.S. in Bioengineering from University of California, Riverside. Currently, he is investigating how protein chaperones and co-chaperones induce disassembly of large macromolecular complexes by employing synthetically reconstituted Clathrin complexes in vitro using advanced single-molecule imaging methods.  As an IDAC fellow, he is developing advanced quantitative tools to: (1) probe the disassembly kinetics of protein complexes with single-molecule sensitivity, and to (2) study fast cellular processes using lattice light-sheet microscopy.

David Hildebrand
PhD Candidate at Engert Lab
The Biological Labs 16 Divinity Ave Cambridge, MA 02138

David is developing methods for investigating neuronal circuit connectivity using large-scale serial-section electron microscopy. His work with IDAC involves co-registering these electron micrographs, analyzing their content, and corresponding the data with optical imaging modalities to combine multiple sources of information.

Remigio Picone
Postdoctoral Fellow at David Pellman's laboratory
450 Brookline Avenue, Mayer 663 Boston, Massachusetts 02215

Remigio Picone is currently a postdoctoral fellow at David Pellman's laboratory of Harvard Medical School/Dana-Farber Cancer Institute. At Dr. Pellman’s lab Remigio is investigating the consequences of centrosome amplification in cancer.  Recently, Pellman's lab has determined that centrosome amplification has a striking aneuploidy-independent ability to promote cell invasion --- an effect that is remarkably similar to that of introducing a bona fide breast cancer oncogene, ErbB2. Remigio has started to make inroads towards understanding the underlying molecular mechanism, and has obtained evidences that increased Rac1 GTPase activation, triggered by increased centrosomal microtubule nucleation, makes a major contribution.

Shay Neufeld
Fellow
LHRRB building, room 302
(617) 432-1893

Shay is a neuroscience graduate student in the Sabatini Lab at Harvard Medical school. He is interested in how the brain computes which actions to select or suppress in a world that is constantly changing. Currently, he is imaging the activity of hundreds of neurons simultaneously while mice flexibly adapt new strategies to maximize rewards. At IDAC, Shay is working to extract neural activities from the large, noisy image datasets, register the signals to specific classes of neurons, and apply appropriate quantitative techniques to gain insight into the relationship between the neural activities and how the mouse behaves.

Staff Alumni

Tiao Xie
Former IDAC deputy director, currently at Definiens AG

Before establishing IDAC, Tiao worked as the image analyst in the ICCB-Longwood Screening Facility at Harvard Medical School for five years. He received his Ph.D. in Computational Chemistry from Emory University. Since then, he has been working on automated image analysis and is specialized in high-content analysis. His experience includes giving advice on design of imaging experiments, providing image analysis software trainings, and developing customized image analysis solutions in MATLAB.

Yichao Joy Xu
Former IDAC software engineer, currently CEO at Xito Technologies Inc.

Joy worked at IDAC from 2013 to mid-2015 as a software engineer, shen then started her adventures in building her startup. She currently is the CEO of Xito Technologies Inc.(CN Name:Xitiou), developing and shipping a tracker called Baryon, and the HERE APP for Baryon for group activity tracking. More info can be found on www.baryon.io.

Fellows Program Alumni

Somponnat (Pat ) Sampattavanich
Former IDAC fellow, currently group leader at Mahidol University

Dr.Somponnat Sampattavanich is currently a faculty member at Mahidol University, Faculty of Medicine Siriraj Hospital, Thailand.  He has initiated the Siriraj Initiative is Systems Pharmacology (sisyspharm.org), applying live cell microscopy and high-content analysis for research work on precision oncology and tropical diseases.  Current research areas include 1) creating drug response library for liver fluke-induced cholangiocarcinoma, 2) developing cell lines with live biosensors for drug screening at single-cell level and 3) investigating the roles of FoxO3a/FoxM1 axis on anti-cancer drug response. 

Pontus Nordenfelt
Postdoctoral Research Fellow at Springer Laboratory
3 Blackfan Street - Room 3117a Boston, MA 02115
(617) 713-8237

Pontus primary position is as a Postdoctoral Research Fellow in the Lab of Tim Springer at Harvard Medical School, and is since June 2013 a joint Fellow with IDAC. Before this, he received his Ph.D. in Cell Biology from Lund University, Sweden. In the past few years, Pontus has focused more and more on advanced imaging, in part as being trained in the Physiology Course at Woods Hole in 2012, and this has led to the need for learning and developing image analysis techniques. At IDAC, Pontus is working on analysis of high-content fluorescence emission anisotropy, FRET biosensors and bright-field cell migration.